MyoKardia HCM Drug Has Success in Cats

MyoKardia’s experimental drug MYK-461, currently in Stage 2 trials for humans, has now been shown to eliminate left ventricular obstruction in five cats with HCM. It has already been shown to inhibit traits of HCM in mice.

Addressing these findings, Associate Professor Joshua Stern, chief of the Cardiology Service at the University of California, Davis, veterinary hospital, stated:

“There has been little to no progress in advancing the treatment of HCM in humans or animals for many years,” Stern said. “This study brings new hope for cats and people.

Based on these positive results, U.C.Davis is hoping to conduct a clinical trial of MYK-461 to determine whether it could become the standard of care for cats with HCM.

The full text of the article published in Plos One can be found here.

6 thoughts on “MyoKardia HCM Drug Has Success in Cats

  1. I would love to have more information on clinical trials available for cats. My eight-year-old cat was diagnosed in January with HCM. He’s always been a big normal healthy active cat is currently on the Lasix and an ace in Hibbe I would love to have more information on clinical trials available for cats. My eight-year-old cat was diagnosed in January with HCM. He’s always been a big normal healthy active cat is currently on Lasix and an ace inhibitor. This drug sounds so promising, I would like to buy him some time.

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  2. I would love to have more information on clinical trials available for cats. My eight-year-old cat was diagnosed in January with HCM. He’s always been a big, normal, healthy, active cat is currently on Lasix and Benazepril. This new drug sounds so promising, I would like to buy him some time.

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  3. I already lost two of my loves to this vicious disease, n now my 2 year old Sphynx Daisy B. Has it, it has progressed significantly since her last scan 4 months ago. We’d do anything to be able to get into the trial. We live in New n have NO problem coming to you. We need to try anything that can possibly save her life. She’s just a baby. Please help us to help her. All we can do is try! We need to attempt trying this drug. I beg you!
    Thank you!

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    1. We are not running the study. HCMBeat is just a news blog. You can contact your veterinarian and ask if they are aware of any studies going on in cats with mavacamten. You could also try contacting MyoKardia and asking the same question.

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